June 30, 2006, Newsletter Issue #13: Sporadic ALS

Tip of the Week

Sporadic ALS is the most common form of ALS, especially in North America. It is found within 90 to 95 percent of all people diagnosed with ALS.

During research conducted between 1995-1996 at Johns Hopkins University, it was discovered that 42 percent of sporadic ALS cases have an EAAT2 protein defect, which is responsible for regulating glutamate levels. The remaining ALS cases are familial and Guamanian ALS.

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